Designing of Potential Polyvalent Vaccine Model for Respiratory Syncytial Virus by System Level Immunoinformatics Approaches
نویسندگان
چکیده
منابع مشابه
Characterization of an experimental vaccine for bovine respiratory syncytial virus.
Bovine respiratory syncytial virus (BRSV) and human respiratory syncytial virus (HRSV) are major causes of respiratory disease in calves and children, respectively, and are priorities for vaccine development. We previously demonstrated that an experimental vaccine, BRSV-immunostimulating complex (ISCOM), is effective in calves with maternal antibodies. The present study focuses on the antigenic...
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Human respiratory syncytial virus (HRSV) is a major cause of severe respiratory tract illnesses in infants and young children worldwide. Despite its importance as a respiratory pathogen, there is currently no licensed vaccine for HRSV. Following failure of the initial trial of formalin-inactivated virus particle vaccine, continuous efforts have been made for the development of safe and efficaci...
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Although RSV has been a high priority for vaccine development, efforts to develop a safe and effective vaccine have yet to lead to a licensed product. Clinical and epidemiologic features of RSV disease suggest there are at least 4 distinct target populations for vaccines, the RSV naïve young infant, the RSV naïve child ≥ 6 months of age, pregnant women (to provide passive protection to newborns...
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Respiratory Syncytial Virus (RSV) is a major cause of severe lower respiratory tract infections in infants and children, leading to hospitalization of an estimated >3 million children under the age of 5 annually [1]. Despite such staggering figures, there is currently no licensed RSV vaccine. In the 1960s, a formalin-inactivated RSV vaccine candidate disastrously led to exacerbated disease [2]....
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Background and Objective: This study was performed to investigate long-term complications of Respiratory Syncytial Viral infections in patients admitted to Ali Asghar Hospital with acute respiratory infections who presented to follow-up outpatient clinics 6 months to 3 years after discharge, between years 2009 and 2011. Methods: In this retrospective observational study that was performed in a...
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ژورنال
عنوان ژورنال: BioMed Research International
سال: 2021
ISSN: 2314-6141,2314-6133
DOI: 10.1155/2021/9940010